Effective host response toFrancisella tularensisrequires functional mast cells
نویسندگان
چکیده
منابع مشابه
Response to C3a, mast cells, and asthma.
This is in response to a “Letter to the Editor (1)” by Dr. Bradding regarding our manuscript entitled “Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact” that was published in your journal recently (2). Dr. Bradding contends that our manuscript, which utilizes a C3a-responsive human mast cell line, is misleading because “it ignores wealth of cons...
متن کاملMast cells initiate early anti-Listeria host defences.
The Gram-positive bacterium Listeria monocytogenes (L. m.) is the aetiological agent of listeriosis. The early phase listeriosis is characterized by strong innate host responses that play a major role in bacterial clearance. This is emphasized by the fact that mice deficient in T and B cells have a remarkable ability to control infection. Mast cells, among the principal effectors of innate immu...
متن کاملMast cells impair host defense during murine Streptococcus pneumoniae pneumonia.
BACKGROUND Streptococcus pneumoniae is the most common causative pathogen in community-acquired pneumonia. Mast cells (MCs) are located mainly at the host-environment interface where they function as sentinels. OBJECTIVE Our goal was to study the role of MCs during pneumonia caused by S. pneumoniae. METHODS Lung tissue of patients who had died from pneumococcal pneumonia or a nonpulmonary c...
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ژورنال
عنوان ژورنال: Future Microbiology
سال: 2008
ISSN: 1746-0913,1746-0921
DOI: 10.2217/17460913.3.5.503